Impact of peritoneal dialysis strategy on technique and patient survival

Abstract Purpose To evaluate the impact of peritoneal dialysis (PD) strategy on technique and patient survival. Methods Retrospective single-center study conducted consecutive patients with chronic kidney disease (CKD) who underwent PD between January 2009 December 2019. Study sample was stratified in four different groups according to [automated (APD) or manual (CAPD)] Icodextrin use (yes versus no). The primary end-points were survival both patient. Results Five-hundred thirty-one included analysis. Mean age 60.6 ± 14.6 years, 68.4% (363) men, 34.8% (185) had diabetes. median time 19 [15] months. One-hundred eighty-five (34.8%), 96 (18.1%), 99 (18.7%), 151 (28.4%) CAPD/No-Icodextrin; CAPD/Icodextrin; APD/No-Icodextrin; APD/Icodextrin groups, respectively. Throughout study, 180 (33.9%) RT, 71 (13.4%) changed HD; died. Age (Hazard ratio, HR:0.975; 95% confidence interval, CI: 0.960–0.990, P = 0.001) incidence early infection (HR:2.440, 95%CI: 1.453–4.098), associated survival; while (HR: 1.029; 1.013–1.045, < 0.001); Charlson Index (HR:1.192; 1.097–1.295, icodextrin 0.421; 0.247–0.710, 0.499; 0.322–0.803, 0.005) Conclusions a positive survival, older higher negative one. significantly impacted